My wife has seen Tunemakers being sold at department stores in Japan, so she was excited to try this product and had high hopes. My wife has always had a lot of dead skin cells around her mouth, from her nose to her chin. Her skin feels somewhat keratinized there, so she exfoliates this area weekly, but still gets a lot of dead skin there, and the skin never gets as soft as the rest of her face. After her first use of the Tunemakers Extract with fruit acid, her skin actually felt softer. So she added a few drops directly to her skin before going to be, and did not experience any irritation. The next morning, her skin felt noticeably softer. This extract can also be used as an exfoliator by rinsing off after use. This only takes a few drops at a time, so the $17.99 price for 0.34 fluid ounces is a reasonable value. The manufacturer says the bottle is good for 50 days, if you use 1-3 drops, twice a day. She loves it!